Redefining bone infection treatment with advanced nanotechnology
‘Inborn’ designs Injectable Bone gels for Regenerative Nanomedicine. Its Nanoparticle-Based Gel (NBG) offers an advanced therapy for local, and intracellular delivery of antibacterial agents for treatment of recurrent bone infectionsN
What is Osteomyelitis?
1 in 5 mortality risk without prompt treatment
Osteomyelitis is a progressive inflammatory disease resulting in bone destruction. It has increasing prevalence, represents a major financial burden for health systems and affects the quality of life of the patients and their families
ABOUT US
Pioneering solutions: From lab to patient care
Born from a vision at Regenerative Biomaterials group, Inborn BioMedical was co-founded by entrepreneurs committed to translating advanced research into impactful solutions for patients. Our NBG harnesses cutting-edge nanotechnology to deliver effective, safe, and long-lasting antibiotic therapy, addressing the unique challenges of bone infections. Driven by this goal, Inborn BioMedical bridges the gap between innovative science and real-world medical needs.
Our technology
Inborn’s Nanoparticle-Based Gel (NBG) is a paste-like gel engineered with hydroxyapatite and gelatin nanoparticles, designed to combat Osteomyelitis effectively. Our gel can be applied directly to the infection site, minimizing systemic side effects and enabling a controlled release of antibiotics.
Patented methodologies in nanoparticle preparation
Spherical hydroxyapatite nanparticles
Proprietary preparation method for Spherical Hydroxyapatite (sHA) nanoparticles
Spherical gelatin nanoparticles
Proprietary preparation method for Spherical Gelatin (sGel) nanoparticles
“Prosthetic joint infections are a devastating complication after primary and revision arthroplasty operations. Traditional treatment methods require multiple surgeries and long-term antibiotic regimens with high morbidity and mortality, placing a significant burden on patients and the healthcare system.”
Dr. Wim Rijnen, MD
Orthopaedic surgeon, Radboudumc
“Inborn’s nanoparticle-based gel is cyto- and biocompatible, and its therapeutic efficacy has been convincingly confirmed in preclinical studies. Consequently, this novel gel creates a beneficial environment for cell infiltration, migration, and tissue remodeling. Moreover, its capacity for intracellular delivery of antibacterial agents is unique and offers new opportunities for the design of novel biomaterials with superior antibacterial efficacy."
Prof. Sander Leeuwenburgh
Regenerative Biomaterials, Radboudumc
QUESTIONS?
Whether you’re curious about our technology, Osteomyelitis, potential devliery options or even collaborations, we’re here to answer any questions.